G-Tech Medical in collaboration with Stanford hospital researchers are conducting a study to assess whether continuous monitoring of postoperative gastrointestinal myoelectric activity after pancreaticoduodenectomy is reproducible and can identify patients that may be at risk for developing delayed gastric emptying (DGE). DGE is a frustrating complication of pancreaticoduodenectomy often requiring prolonged nasogastric decompression which causes patient discomfort, increases risk of aspiration events and prolongs hospital stay. Since, the pathophysiology for DGE is unclear, there is no current way to predict which patients DGE is likely to occur in. Early clinical results presented at DDW17 support the promising idea that objective data provided by the patches will allow identification of patients at risk for DGE and can help guide timing of oral intake by "gastric readiness".
El Camino Hospital
G-Tech Medical in collaboration with El Camino Hospital is conducting a feasibility study for assessing and recording gastrointestinal (GI) myoelectric activity in patients for early detection of post-operative ileus (POI) in patients who undergo gastrointestinal surgery and differentiating the myoelectric signals from those who have normal post-operative return of GI function. A POI is a frequent, frustrating occurrence for patients who undergo GI surgery. Physiologic postoperative ileus is generally a benign condition that resolves without serious sequelae. However, when ileus is prolonged, it leads to patient discomfort, dissatisfaction, and prolonged hospitalization, and must be differentiated from mechanical bowel obstruction or other postoperative complications. Early detection of a POI, prior to patient experiencing symptoms will allow for earlier intervention and possibly decrease the LOS in patients who develop a POI.
The Parkinson’s Institute is conducting a GI natural history study, monitoring the progression of gastrointestinal symptoms in patients with or at risk of developing Parkinson’s Disease (PD) with the G-Tech patch system as one of the tests. It is estimated that gastrointestinal dysfunction in Parkinson’s disease may occur in up to 80% of patients. It is hoped that this study may lead to earlier diagnosis of Parkinson’s disease, improved patient care, as well as identifying new ways to test investigational drugs that may be neuroprotective and serve as future treatments for these symptoms. Over 100 patients have used the “at home” G-Tech Patch System, measuring motor activity of the digestive organs continuously and unobtrusively over multiple days and under realistic physiological conditions as they go about their normal daily activities.
G-Tech conducted an IRB approved clinical trial as a feasibility study for monitoring and recording gastrointestinal myoelectric activity in subjects with suspected or diagnosed Irritable Bowel Syndrome (IBS) and reports of GI pain and asymptomatic subjects without IBS And GI pain. A total of 102 tests were conducted with both controls and patients referred by partner gastroenterologists. The test used traditional wired EKG style hardware; three EKG systems in parallel, with thirty electrodes in a grid across the abdomen. Data was acquired for a three hour period with the subjects having fasted for at least four hours and then fed a standardized 700 kCal meal one hour into the test. This study showed that it is possible to measure electrical signals from the digestive system non-invasivelyand correlate those electrical signals to motor activity of the stomach, small intestine and colon.